Neil Anthony, PhD
Bits 2 Binders
BioML - LEAH Labs challenge using AI models to generate CD20 Chimeric Antigen T-Cell (CAR-T) therapy binding motifs.
PyMOL - CD20 Protein
Transmembrane CD20 protein structure visualization and candidate residue identification.
Researching the structure of CD20, in particular, it's extra cellular matrix (ECM) residues to select potential key amino acids for binding surface targets.
RFDiffusion Model
Using RFDiffusion model to predict > 80 amino acid binding partner. Candidate binding structure, amino acid selection and weighting, together with diffusion model parameters allowed for generation of a binding partner backbone structure.
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